3. NSI-189 Working principle and clinical research
The drug is still undergoing active research, so we don’t totally know how it works. However, when tested on adult mice, NSI-189 has been shown to increase their hippocampal volume by 20%.
Further in vitro and in vivo studies on human hippocampal stem cells showed that NSI-189 stimulated neurogenesis (the formation of new brain cells).
This is important because the hippocampus is the part of your brain that transforms your short-term memories into long-term memories.
The hippocampus also plays critical roles in your spatial navigation and in your mood regulation.
In other words, NSI-189 may be able to increase memory while also boosting spatial thinking and improving your mood. That’s why people are getting excited about the drug.